[16] The same format as last year was used:[4] The draw of the tournament was held on 16 October 2015 during the CONMEBOL Executive Committee meeting at the Hyatt Hotel in Santiago, Chile.

UAI Urquiza São José Formas Íntimas Ferroviária Colo-Colo Real Pasión Espuce Cerro Porteño Universitario San Martín de Porres Colón Estudiantes de Guárico The schedule of the tournament was announced on 20 October 2015.

If tied on points, tiebreakers would be applied in the following order:[4] All times local, COT (UTC−5).

São José v Cerro Porteño was suspended after 50 minutes due to heavy rain.

Catalina Usme won the top-scorer award with eight goals in three matches.