[4] It was held at the Circuit of the Americas in Elroy on April 12, 2015.

In the MotoGP class, Repsol Honda's Marc Márquez took his first pole position of the season, and he ultimately went on to win the race, his third victory in as many years at the circuit.

[5] For the first time since the 2014 Aragon Grand Prix, three different manufacturers were represented on the podium; behind Márquez was Ducati's Andrea Dovizioso, who prevailed in a battle with Yamaha's Valentino Rossi, who finished in third place.

In his 200th premier class start, local hero Nicky Hayden could only finish in thirteenth, while numerous riders retired from the race – Pol Espargaró collided with Scott Redding, with caused both riders to retire from the race, while Yonny Hernández, Mike Di Meglio and Stefan Bradl all crashed before the halfway mark.

Below are the standings for the top five riders and constructors after round two has concluded.