The 2015 Western Kentucky Hilltoppers football team represented Western Kentucky University (WKU) in the 2015 NCAA Division I FBS football season as members of the East Division of Conference USA.

Led by second year head coach Jeff Brohm, they played their home games at Houchens Industries–L.

They finished the season 12–2, 8–0 in C-USA play to be champions of the East Division.

They led the NCAA in Passing Efficiency, tied the school record for victories and were also ranked in the FBS AP Top 25 for the first time in program history.

The Hilltoppers will host CUSA foes Florida Atlantic, Louisiana Tech, Marshall, and Middle Tennessee, and will travel to Florida International (FIU), North Texas, Old Dominion, and Rice.