The 2004 Louisville Cardinals football team represented the University of Louisville in the 2004 NCAA Division I-A football season.

The team, led by Bobby Petrino in his second year at the school, played their home games in Papa John's Cardinal Stadium.

They were invited to and won the Liberty Bowl, defeating Western Athletic Conference champion Boise State 44–40.

The Cardinals finished the 2003 season with a 9–4 record, losing to Miami (OH) in the 2003 GMAC Bowl.

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