The women's 4 × 100 metres relay at the 2015 World Championships in Athletics was held at the Beijing National Stadium on 29 August.

Jamaica rested two, Veronica Campbell-Brown and Elaine Thompson, but not their superstar Shelly-Ann Fraser-Pryce, in order to make six girls eligible for medals.

USA ran their A team, to assure qualification but not resting their workhorse Allyson Felix even though Tori Bowie, Dezerea Bryant and Kaylin Whitney had been listed as their entries,[3] unlisted Jasmine Todd anchored.

Kseniya Ryzhova left too early and Russia never made a handoff, while USA looked to proportionally hold their own against the stagger through the backstretch with Felix.

Desiree Henry ran away from the others and was closing on Hackett,[4] while the Dutch team's illegal handover earned them a disqualification.