They played their home games at Bryant–Denny Stadium in Tuscaloosa, Alabama and were led by tenth year head coach Nick Saban.

They finished the season 14–1, were SEC champions and advanced to the College Football Playoff National Championship game, for the second consecutive year, where they were defeated by Clemson.

Notable departures from the 2015 squad included Prior to National Signing Day on February 3, 2016, eight players enrolled for the spring semester in order to participate in spring practice and included six former high school seniors and two junior college transfers.

Sources: Alabama had seven returning players on offense, five on defense and five on special teams that started games in 2015.

Alabama faced all six Western Division opponents: Arkansas, Auburn, LSU, Mississippi State, Ole Miss, and Texas A&M.

at Bryant-Denny Stadium • Tuscaloosa, AL at Vaught–Hemingway Stadium • Oxford, MS The Crimson Tide began conference play against Ole Miss, who entered the game on a two-game winning streak against Alabama, their longest winning streak in the series.

|- Key: POS: Position, SOLO: Solo Tackles, AST: Assisted Tackles, TOT: Total Tackles, TFL: Tackles-for-loss, SACK: Quarterback Sacks, INT: Interceptions, BU: Passes Broken Up, PD: Passes Defended, QBH: Quarterback Hits, FF: Forced Fumbles, FR: Fumbles Recovered, BLK: Kicks or Punts Blocked, SAF: Safeties Overall awards

Howard – TE Cam Robinson – OL Calvin Ridley – WR Alphonse Taylor – OL Ross Pierschbacher – C Jonathan Allen – DL Reuben Foster – LB Eddie Jackson – DB Preseason All-Americans Each year several publications release lists of their ideal "team".