The 2016 Fergana Challenger was a professional tennis tournament played on hard courts.

It was the 17th edition of the tournament for men which was part of the 2016 ATP Challenger Tour, offering a total of $50,000 in prize money, and the sixth edition of the event for women on the 2016 ITF Women's Circuit, offering a total of $25,000 in prize money.

It took place in Fergana, Uzbekistan, on 13–19 June 2016.

[1] The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following player received entry by a junior exempt: