Voters will select candidates for all local positions: a town mayor, vice mayor and town councilors, as well as members of the Sangguniang Panlalawigan, the vice-governor, governor and representatives for the four districts of Laguna, including the newly created Biñan lone district.

On October 2, 2015, on the LP Provincial convention in Santa Cruz, Laguna, and birthday party of Representative Benjie Agarao, which attended by presidential candidate Mar Roxas and senatorial candidate Francis Tolentino, which become controversial that Tolentino sent girl group Play Girls for a dance show, which was criticized by netizens due to obscene performance.

However, they will support, Alan Peter Cayetano, Bongbong Marcos or Antonio Trillanes IV as their Vice President—but all they're failed to get that party's nomination and instead running independents; Cayetano and Marcos are running mates for respective presidential candidates, Rodrigo Duterte of PDP–Laban and Miriam Defensor-Santiago of People's Reform Party, while Trillanes is supporting Grace Poe's presidential bid.

However, Hernandez chose to support Roxas' running mate for vice president, Camarines Sur's Third District representative Leni Robredo.

Former 4th District Congressman Edgar San Luis, who ran for governor in 2013 but lost to Ejercito and decided not to run to give way for Hernandez, bolted the Liberal Party and moved to National Unity Party (even the NUP was already in coalesce with the Liberal coalition, known as "Koalisyon ng Daang Matuwid").

Incumbent Mayor Marlyn Alonte-Naguiat will run for the newly created Lone District unopposed.

His opponents are incumbent Vice Mayor Rafael Campos, Michael Casacop and Eugenio Ynion, Jr.

Incumbent Mayor Jovit Reyes of UNA seeks for reelection against councilor Oscar "Ka Popoy" Rafanan of Liberal Party.

Incumbent Vice Mayor Alberto "Jun" Astoveza Jr. of LP will run for reelection against UNA's bet councilor Al Pajarillo.