The Thundering Herd played their home games at the Joan C. Edwards Stadium in Huntington, West Virginia, and competed in the East Division of Conference USA (C–USA).

They were led by seventh-year head coach Doc Holliday.

The 2016 schedule consists of 7 home and 5 away games in the regular season.

The Thundering Herd will host C–USA foes Charlotte, Florida Atlantic, Middle Tennessee, and Western Kentucky (WKU), and will travel to Florida International (FIU), North Texas, Old Dominion, and Southern Miss.

[1] The team played four non–conference games, three home games against Akron from the Mid-American Conference (MAC), Louisville from the Atlantic Coast Conference (ACC), and Morgan State from the Mid-Eastern Athletic Conference, and travel to Pittsburgh from the ACC.