The 2016 Norfolk State Spartans football team represented Norfolk State University in the 2016 NCAA Division I FCS football season.

They were led by second-year head coach Latrell Scott and played their home games at William "Dick" Price Stadium.

They were a member of the Mid-Eastern Athletic Conference (MEAC).

They finished the season 4–7, 3–5 in MEAC play to finish in a three way tie for seventh place.