The 2017–18 season was Guadalajara's first competitive season and first season in the Liga MX Femenil, the top flight of Mexican women's football.

Guadalajara won the inaugural Liga MX Femenil tournament, defeating Pachuca in the Apertura 2017 final.

[1] For the Clausura 2018 tournament, the team finished fourth overall, but failed to qualify for the playoffs.

Source: Competitions