[3][4][5] On 3 May 2017, Palafox made her debut for Guadalajara in a 6–1 loss to Pachuca in the Copa MX Femenil.
On 29 July, she made her first Liga MX Femenil appearance in a 3–0 home victory against Atlas.
[6] In the first leg of the 2017 Apertura final on 20 November, Guadalajara were beaten 2–0 by Pachuca, but two goals from Arlett Tovar and one from Palafox helped them win 3–0 the second leg on 24 November, and consequently the first ever Liga MX Femenil title.
She made one appearance in the tournament in a 2–1 loss to the United States on 23 January 2018.
This biographical article related to women's association football in Mexico is a stub.