[1] This was the first time in history that the ALCS and NLCS teams were from the four most populous U.S. cities: New York, Los Angeles, Chicago, and Houston.

In a pitcher's duel, Dallas Keuchel and Masahiro Tanaka allowed no runs through the first three innings before the Astros scored in the bottom of the fourth.

He struck out four of six but allowed a home run to Greg Bird before striking out Jacoby Ellsbury swinging to end the game.

Carlos Correa opened the scoring in the fourth inning with a home run off of starter Luis Severino that barely scraped over the right field wall.

[16] In the bottom of the second inning, Todd Frazier opened the scoring with a three-run home run after two two-out singles off of Charlie Morton.

After a leadoff ground-rule double and two-out walk, Chase Headley's RBI single made it 4–0 Yankees.

A hit-by-pitch to Brett Gardner loaded the bases before Morton was relieved by Will Harris, who threw a wild pitch to let Frazier score before a three-run home run by Aaron Judge made it 8–0.

In the top of the ninth inning, Dellin Betances entered in relief only to walk the first two batters before getting pulled for Tommy Kahnle.

A single by Cameron Maybin loaded the bases, then one out later, walk to Alex Bregman forced in a run, but Jose Altuve hit into the game-ending double play as the Yankees' won Game 3 8–1.

With the bases loaded in the top of the sixth on two walks and a catcher's interference call, Yuli Gurriel cleared them with a double off of David Robertson to put the Astros up 3–0.

The next inning, a Starlin Castro fielding error allowed Marwin González, who doubled, to score, increasing the lead to 4–0.

Chris Devenski entered in relief only to allow a triple to Didi Gregorius and a sacrifice fly to Gary Sánchez, cutting the lead to 4–2.

In the bottom of the eighth, Todd Frazier and Chase Headley both singled, with the latter tripping on his way to second base and evading Jose Altuve's close tag to remain safe at second.

In the bottom half of that inning, Starlin Castro hit a two-out double and was driven in by Greg Bird's single.

[21] In the winner-take-all game to decide the AL pennant winner, Aaron Judge made a leaping catch to rob Yuli Gurriel of a solo homer in the bottom of the second inning.

Lance McCullers Jr. entered in relief, pitching four scoreless innings to close out the game and earn his first career save.

[24] MLB opened an investigation into this sign stealing allegation and found the Astros used technology to cheat during their 2017 championship season and parts of 2018, as well.

[31] Astros owner Jim Crane responded by calling his comments odd (as the Yankees were found to have done their own scheme in 2015), adding, "There’s the letter, and you were doing it, too.

The Astros consecutive ALCS streak ended at seven in 2024 when they were defeated by former manager AJ Hinch and the Detroit Tigers in the AL Wild Card Series.

Carlos Beltrán, the only player named in the commissioner's report for his role in the Astros sign-stealing scandal, was hired by the Yankee's YES Network as a game analyst before the 2022 season.