The 2017 CAF Confederation Cup knockout stage was played from 8 September to 25 November 2017.
[1] A total of eight teams competed in the knockout stage to decide the champions of the 2017 CAF Confederation Cup.
In the knockout stage, the eight teams played a single-elimination tournament.
If the aggregate score was tied after the second leg, the away goals rule would be applied, and if still tied, extra time would not be played, and the penalty shoot-out would be used to determine the winner (Regulations III.
[1][3][4] The calendar was amended from the original one for the following dates:[4] The bracket of the knockout stage was determined as follows:[2] The order of legs for the semi-finals and final was decided by an additional draw held after the group stage draw on 26 April 2017, 14:00 EET (UTC+2), at the CAF Headquarters in Cairo, Egypt.