The Packers started out strong, compiling a 4–1 record, but during a week 6 game against their division rival Minnesota Vikings, the Packers lost starting quarterback Aaron Rodgers to a collarbone injury and eventually ended with a 7–9 record despite his attempted return in a loss to the Carolina Panthers in Week 15.

On the Packers' first drive, Aaron Rodgers threw an interception that was returned for a touchdown, but an illegal block in the back penalty negated the score.

In the third quarter, Mike Daniels forced a fumble that Green Bay recovered at the Seattle 6-yard line, and Ty Montgomery ran in for a touchdown on the following play, giving the Packers a lead they wouldn't relinquish after that.

Later Rodgers caught the Seahawks with 12 men on the field and capitalized on the free play by throwing a 32-yard touchdown to Jordy Nelson.

The Packers only surrendered two field goals to Seattle for the rest of the game, giving a strong defensive showing in the season opener.

In a rematch of the 2016 NFC Championship game earlier that year, the Falcons defeated the Packers to open up their new stadium.

The teams exchanged opening drive touchdowns, but with both starting tackles out of the game due to injury, the Packers' offense failed to keep pace.

On the ensuing play Aaron Rodgers threw an interception to Desmond Trufant that lead to a Falcons touchdown, making the score 24–7 at halftime.

On a one-yard pass to Ty Montgomery late in the fourth quarter, Aaron Rodgers recorded his 300th career touchdown.

Taking advantage of several Chicago miscues, including three turnovers and a missed field goal, the Packers rolled to a convincing win over their rivals, with Aaron Rodgers throwing four touchdown passes.

The Packers lost Aaron Rodgers to a shoulder injury early in the game after he took a big hit from Minnesota linebacker Anthony Barr.

After the game, Mike McCarthy announced that due to Rodgers' injury, Hundley would be given the starting quarterback position "indefinitely."

Rookie Aaron Jones rushed for 131 yards on 17 carries and a touchdown, his second 100-yard game in three career starts.

After the two teams exchanged field goals, the Saints took the lead for good on an 8-play, 55 yard drive that ended with a 1-yard touchdown rush from Drew Brees.

Green Bay's comeback effort was thwarted when Brett Hundley threw an interception to safety Kenny Vaccaro on the ensuing drive.

Lions quarterback Matthew Stafford played an efficient game, registering two touchdowns with no interceptions, resulting in a 132.4 passer rating.

In his second career start, Brett Hundley once again failed to attack the defense downfield or establish a comfortable pocket presence.

After failing to apply a solid pass rush in the previous two games, the Packers' Defense sacked Bears rookie Quarterback Mitchell Trubisky five times, with linebacker Nick Perry accounting for three.

Packers' running backs Aaron Jones and Ty Montgomery left with knee and rib injuries, respectively, allowing rookie Jamaal Williams to see his first action in the NFL.

Field position was key as the Ravens' special teams often kept the Packers starting drives deep in their own territory.

After a one-minute drive led to a punt, the Steelers drove 35 yards down the field in 17 seconds in the waning moments of the fourth quarter.

The Packers started overtime with the ball, and Aaron Jones capped off the comeback win with a 20-yard touchdown run.

In overtime, Browns quarterback DeShone Kizer threw a costly interception to Josh Jones, and Adams took a screen pass to the end zone, improving the Packers record to 7–6 and setting the stage for Aaron Rodgers' comeback.

The Vikings played conservatively all night, and like the Ravens, won the game with expert field position and forced Brett Hundley to make mistakes.