The Tigers played their home games at the Liberty Bowl Memorial Stadium in Memphis, Tennessee and competed in the West Division of the American Athletic Conference.

They finished the season 10–3, 7–1 in AAC play to be champions of the West Division.

The 2017 schedule consists of 7 home and 5 away games in the regular season.

The Tigers will host AAC foes East Carolina, Navy, SMU, and Tulane, and will travel to UConn, Houston, Tulsa, and UCF.

Memphis was supposed travel to Georgia State from the Sun Belt Conference before Hurricane Irma caused their conference opener at UCF to be rescheduled over the Georgia State game.