The draw for play-offs took place on 24 May 2019[40] and the games will be played on 4 and 8 June 2019.

[41] Kolos Kovalivka won 2–0 on aggregate and were promoted to the 2019–20 Ukrainian Premier League.

Chornomorets Odesa were relegated to the 2019–20 Ukrainian First League Karpaty Lviv won 3–0 on aggregate and retained their spot in the 2019–20 Ukrainian Premier League.

Volyn Lutsk remained in the 2019–20 Ukrainian First League Due to fan violence at the game and attack on referee, the original score 1–3 was scratched and replaced with technical score 0–3 loss to Volyn and win for Karpaty.

Additionally, the Lutsk department of police started criminal proceedings on the fact of intentional damage to property during the game by the Karpaty fans.