2018–19 Houston Cougars women's basketball team

The season marked the sixth for the Cougars as members of the American Athletic Conference.

They played their home games at Fertitta Center, which reopened on December 1, 2018, after a $60 million upgrade.

The Cougars played their first three non-conference home games at H&PE Arena while construction on Fertitta Center was completed.

They lost to South Florida in the quarterfinals of the American Athletic Conference women's tournament.

They received an at-large bid to the Women's National Invitation Tournament, where they lost to Arkansas in the first round.

Houston in action against SMU