[4] Major network and cable television broadcasting companies, including CBS, NBC, ABC, FOX, ESPN and CNN have all produced events through this arena.

Margenau introduced Gary Porter, as the head coach for the team that would first take the field April 5, 2002 at the Mohegan Sun Arena against the Albany Conquest.

By the time the Connecticut Sun moved in, Val Ackerman was the WNBA president and Mark L. Brown was the chairman of the Mohegan Tribe.

After the conclusion of the 2020 WNBA season, the arena began holding its first events since the pandemic declaration in November 2020, when it hosted a series of college basketball games where fans were not permitted.

On April 21, 2002, the Mohegan Sun Arena hosted the 2002 National Lacrosse League All-Star Game.

The North Division (Calgary Roughnecks, Montreal Express, Ottawa Rebel, Rochester Knighthawks, Toronto Rock, Vancouver Ravens) defeated the South (Albany Attack, Buffalo Bandits, Columbus Landsharks, New Jersey Storm, New York Saints, Philadelphia Wings, Washington Power) by a score of 14–10.

On August 5, 2014, the National Lacrosse League announced that the Philadelphia Wings would move to the Mohegan Sun Arena and be re-branded as the New England Black Wolves for the 2015 season.

[8] On January 11, 2002, Mohegan Sun Arena hosted its first MMA event, UFC 35, headlined by Jens Pulver vs B.J.