The 2018–19 Portland Pilots women's basketball team represented the University of Portland in the 2018–19 NCAA Division I women's basketball season.

The Pilots were led by fifth year coach Cheryl Sorensen.

They played their homes games at Chiles Center and were members of the West Coast Conference.

They lost in the first round of the WCC women's tournament to San Francisco.

On March 12, Cheryl Sorensen has agreed to parted ways.