The 2022–23 Portland Pilots women's basketball team represented the University of Portland in the 2022–23 NCAA Division I women's basketball season.

The Pilots were led by fourth-year coach Michael Meek.

They played their homes games at Chiles Center and were members of the West Coast Conference (WCC).

They defeated in the quarterfinals WCC women's tournament to Loyola Marymount before losing to BYU in the semifinals.

They received an at-large bid to the WNIT they defeated Colorado State in the first round before losing to Oregon State in second round.