The Jackrabbits, led by nineteenth year head coach Aaron Johnston, competed in the Summit League.

They played home games in Frost Arena in Brookings, South Dakota.

They were champions of The Summit League women's tournament and earned an automatic trip to the NCAA women's tournament, where they defeated Quinnipiac and upset Syracuse in the first and second rounds to advanced to their first sweet sixteen appearance where they lost to Oregon.

The Jackrabbits won the 2018 Summit League Tournament defeating North Dakota State in the quarterfinals, Western Illinois in the semifinals, and South Dakota in the Summit League Championship 65–50 earning the Jackrabbits an automatic bid to the 2018 NCAA Division I women's basketball tournament.

During the selection show, the Jackrabbits received an 8 seed in the Spokane region facing the Villanova Wildcats, but lost in overtime 81–74.