Despite a 2–1 defeat to Boston United on 21 April 2018, Salford City became 2017–18 National League North champions after Harrogate Town lost 3–1 to Bradford Park Avenue.
On 24 April, after 97 years as an EFL club, Chesterfield were relegated to the National League following Morecambe's 0–0 draw against Cambridge United.
On 5 May 2018, despite a 3–0 victory against Chesterfield, Barnet became the second club to be relegated from League Two following Morecambe's 0–0 draw against Coventry City, ending their three-year stay in the EFL.
Tranmere Rovers were promoted to League Two on 12 May after a 2–1 victory over Boreham Wood in the playoff final and returned to the EFL after a three-year absence.
Boreham Wood and Sutton United were invited to compete in the 2018–19 Scottish Challenge Cup in a new expansion of that competition as the highest-finishing remaining teams in the division.
Despite staying up on the final day for the past two seasons, it was not to be third time lucky for Guiseley who joined them on 17 April after a 1–0 loss to relegation rivals Barrow.