The 2018 Adriatica Ionica Race/Following the Serenissima Routes was a five-stage men's professional road cycling race.

The general classification was calculated by adding each cyclist's finishing times on each stage.

The leader of the points classification was awarded a red jersey sponsored by Full Speed Ahead.

The climbs were categorized, in order of increasing difficulty, as third-, second-, and first-category and hors catégorie (read: "beyond category").

[20] The final classification was the "Fighting Spirit Prize" given after each stage to the rider considered, by a jury, to have "who struggled in order to achieve results in all the competitive moments of the race or the one who take action to start or carry out the longest breakaway".