It was held at the Autódromo Termas de Río Hondo in Santiago del Estero on 8 April 2018.

The result was Jack Miller (who didn't return to the pits for a tire change) in the first position on the grid and the other riders in formation several rows back.

He was successful in restarting the stalled motorcycle, but race officials ran out and instructed him to return to pit-lane.

After jumping to an early lead, Marc Márquez was issued a ride-through penalty for riding his motorcycle in the opposite direction on the track.

[2] In the closing laps there were multiple passes for the podium positions between Zarco, Rins and Crutchlow as the riders struggled with tire wear and damp patches on the track.