The 2018 Brickyard 400, branded as Big Machine Vodka 400 at the Brickyard, is a Monster Energy NASCAR Cup Series race held on September 10, 2018 at Indianapolis Motor Speedway in Speedway, Indiana.

It is located on the corner of 16th Street and Georgetown Road, approximately six miles (10 km) west of Downtown Indianapolis.

Qualifying for Saturday was cancelled due to rain and Kyle Busch, the point leader, was awarded the pole as a result.

Rick Allen and Steve Letarte had the call in the booth for the race.

Dave Burns, Parker Kligerman, Marty Snider and Kelli Stavast reported from pit lane during the race.