The 2018 Charlotte Independence season was the club's fourth season of existence, and their fourth in the United Soccer League, the second tier of American soccer.

In the 2017 USL Playoffs, Charlotte were bested in the first round by the Rochester Rhinos.

Elsewhere, the Independence reached the third round of the 2017 U.S. Open Cup, losing 1–4 to NASL outfit, North Carolina FC.

Win Draw Loss Upcoming fixture Last updated: 25 September 2018.

Source: Matches Win Draw Loss Upcoming fixture