The Sox played their home games at Guaranteed Rate Field.

It was the final season for long time PBP announcer Ken Harrelson who retired before the end of the season, and the second of the last for broadcasts on long time FTA broadcaster WGN-TV, the 2018–19 offseason was when it was announced that NBC Sports Chicago, the team's cable partner, will become the de facto official station of the team effective Opening Day 2020 with more game broadcasts there.

No plans are yet to be made regarding the team's future free-to-air television broadcasts, through.

Infielders Coaches Final Stats Players in bold are on the active roster as of the 2022 season.

Note: G = Games played; AB = At bats; R = Runs; H = Hits; 2B = Doubles; 3B = Triples; HR = Home runs; RBI = Runs batted in; SB = Stolen bases; BB = Walks; K = Strikeouts; AVG = Batting average; OBP = On-base percentage; SLG = Slugging percentage; Final stats Players in bold are on the active roster as of the 2022 season.