The 2018 Lafayette Leopards football team represented Lafayette College in the 2018 NCAA Division I FCS football season.

The Leopards were led by second-year head coach John Garrett and played their home games at Fisher Stadium.

The Patriot League released their preseason coaches poll on July 26, 2018, with the Leopards predicted to finish in a tie for fifth place.

[1] The Leopards placed four players on the preseason all-Patriot League team.

Offense Will Eisler – FB Defense Anthony Giudice – DL Jerry Powe – LB Special teams CJ Amill – RS