The 2018 Open de Cagnes-sur-Mer was a professional tennis tournament played on outdoor clay courts.

It was the twenty-first edition of the tournament and was part of the 2018 ITF Women's Circuit.

It took place in Cagnes-sur-Mer, France, on 7–13 May 2018.

The following players received a wildcard into the singles main draw: The following players received entry from the qualifying draw: The following players received entry as lucky losers: