The 2019 Indiana State Sycamores baseball team represented Indiana State University during the 2019 NCAA Division I baseball season.

They were led by head coach Mitch Hannahs, in his 6th season at Indiana State.

The 2018 Indiana State Sycamores baseball team notched a 29–22 (11–10) regular season record and finished tied for third in the MVC Conference standings.

The Sycamores reached the 2018 Missouri Valley Conference baseball tournament, where they were defeated by Missouri State in the semifinals.

Indiana State did not receive an at-large bid to the 2018 NCAA Division I baseball tournament.