The Redbirds played their home games at Duffy Bass Field as a member of the Missouri Valley Conference.
They were led by head coach Steve Holm, in his 1st season at Illinois State.
The 2018 Illinois State Redbirds baseball team notched a 22–28 (9–12) regular season record and finished tied for sixth in the MVC Conference standings.
The Redbirds reached the 2018 Missouri Valley Conference baseball tournament, where they were defeated by Bradley and Dallas Baptist.
Illinois State did not receive an at-large bid to the 2018 NCAA Division I baseball tournament.