The tournament was the culmination of the 2019 Spring Split, the first part of season 9 of the game's competitive scene.

[1][2] "Bring Home The Glory" was the tournament's theme song, put together by Sara Skinner.

Matches of the play-in were held in the VCS Studio in Ho Chi Minh City, matches of the group stage were held in the Vietnam National Convention Center in Hanoi, and playoffs took place in the Taipei Heping Basketball Gymnasium in Taipei.

G2 Esports from Europe defeated Team Liquid from North America 3–0 in the final and brought the region its first MSI championship.

Because of the Regional success in MSI and the World Championship in the two years prior (2017 and 2018), three teams from Europe (LEC), South Korea (LCK), and China (LPL) began in the main Group stage; two teams from North America (LCS) and Taiwan/Hong Kong/Macau (LMS) begin in the second round of the play-in stage; and the eight remaining teams begin in the first round of the play-in stage.