On September 12, 2019, a press conference was held on Orleans Arena.
On September 13, 2019, prejudging and finals for Fitness Olympia, Figure Olympia and Classic Physique were held and livestream via Amazon Prime.
On September 14, 2019, the Men's Physique Olympia and Women's Physique Olympia judging and finals were held in the morning at Las Vegas Convention Center.
Shawn Rhoden, the previous year Mr Olympia 2018, was not allowed to compete for legal reasons, so there was no defending champion this year.
Brandon Curry won his first Mr Olympia title.