[1] Yangon United are the defending champions, while Chinland and Dagon have entered as the promoted teams from the 2018 MNL-2.
Promoted from the 2018 MNL-2 Relegated from the 2018 Myanmar National League Royal Thanlyin decided not to play in 2019 MNL because of finance.
Myanma Posts and Telecommunications signed 3 years contract with MNL.
[3] [4] Note: Flags indicate national team as has been defined under FIFA eligibility rules.
In order to preserve chronological evolvements, any postponed matches are not included in the round at which they were originally scheduled, but added to the full round they were played immediately afterwards.