It determined the national champion for the 2018–19 NCAA Division I women's basketball season.

The game was played on April 7, 2019, at the Amalie Arena in Tampa, Florida, between Notre Dame and Baylor.

Notre Dame, led by 32nd-year head coach Muffet McGraw, finished the regular season with a record of 27–3.

This win put the Fighting Irish in the Final Four, where they beat the Albany Regional champions, No.

Two Notre Dame players were selected to the Chicago Regional all tournament team: Arike Ogunbowale and Jessica Shepard.

Baylor, led by 18th-year head coach Kim Mulkey, finished the regular season with a record of 28–1.

Four Baylor players were selected to the Greensboro Regional all tournament team: Lauren Cox, DiDi Richards, Chloe Jackson, and Kalani Brown.