The Mariners played their twentieth full season and twenty-first overall at newly renamed T-Mobile Park, their home ballpark.
The Mariners entered the season with the longest active playoff drought in the four major North American professional sports and again failed to make their first postseason appearance since 2001.
However, they went 55–92 after their great start, finishing last in the American League West for the first time since 2012 and falling out of the playoffs once again.
The Mariners also set a then-MLB record by using 69 different players during the regular season, which would stand for five years before being broken by the Miami Marlins in 2024.
Infielders Outfielders Coaches Note: G = Games played; AB = At bats; R = Runs; H = Hits; 2B = Doubles; 3B = Triples; HR = Home runs; RBI = Runs batted in; SB = Stolen bases; BB = Walks; AVG = Batting average; SLG = Slugging average Source:[1] Note: W = Wins; L = Losses; ERA = Earned run average; G = Games pitched; GS = Games started; SV = Saves; IP = Innings pitched; H = Hits allowed; R = Runs allowed; ER = Earned runs allowed; BB = Walks allowed; SO = Strikeouts Source:[2]