The Gamecocks played their home games at Williams–Brice Stadium in Columbia, South Carolina, and were led by fourth-year head coach Will Muschamp.

USC also picked up 3 star center, Vincent Murphy from St. Thomas Aquinas High School in Florida.

[8] On May 25, 5 star defensive end Zacch Pickens committed to South Carolina.

[9] Sources: The 2019 SEC Media Days were held July 15–18 in Birmingham, Alabama.

In the preseason media poll, South Carolina was projected to finish in fourth in the East Division.

The Gamecocks hosted SEC foes; Alabama, Kentucky, Florida, and Vanderbilt.

They faced North Carolina in neutral site game in Charlotte, NC, and hosted Charleston Southern (Big South), Appalachian State (Sun Belt), and Clemson (ACC).

“I don’t think anyone could argue against the following statement that South Carolina has the hardest schedule in the country, it is absolutely brutal.

[16] ‡ As part of their penalty for NCAA violations, Tennessee has retroactively vacated its 2019 victory over South Carolina.