The Cowboys were led by sixth-year coach Craig Bohl and played their home games at War Memorial Stadium as a member of the Mountain Division of the Mountain West Conference.

The Cowboys announced an early signing class of 18 high school student athletes on December 19, 2018.

[4] Sources: Wyoming held their annual Brown and Gold Game on April 27.

[5] Listed in the order that they were released Mountain West media days were held on July 23 and 24 at the Cosmopolitan on the Las Vegas Strip.

[9] Quarterback Tailback Fullback Wide receiver Tight end Offensive lineman Defensive lineman Linebackers Defensive backs Placekicker Punter Holder Long snapper Legend Key: SOLO: Solo Tackles, AST: Assisted Tackles, TOT: Total Tackles, TFL: Tackles-for-loss, SACK: Quarterback Sacks, INT: Interceptions, BU: Passes Broken Up, QBH: Quarterback Hits, FF: Forced Fumbles, FR: Fumbles Recovered, BLK: Kicks or Punts Blocked, SAF: Safeties