Wilson grew up in Casper, Wyoming and attended Natrona County High School, where he played defensive back, wide receiver, placekicker and punter on the football team.

[15] He made his debut in the opening game of 2020, recording two tackles as a reserve linebacker against the Los Angeles Chargers.

[16] In Week 3 against the Philadelphia Eagles, Wilson recorded his first career interception off a pass thrown by Carson Wentz during the 23–23 tie game.

[20] On September 26, 2021, Wilson intercepted Pittsburgh Steelers quarterback Ben Roethlisberger twice, along with a game-high 14 tackles in route to a 24-10 victory for the Bengals at Heinz Field in Week 3.

In the AFC Divisional Playoff game against the top seeded Tennessee Titans, Wilson intercepted a tipped throw from Ryan Tannehill mid-field.

This set up an eventual game-winning field goal by Evan McPherson, giving the Bengals their first road playoff win in franchise history, 19-16.

[29] He made a crucial interception in the fourth quarter of the Bengals' Week 8 against the San Francisco 49ers, returning it for 16 yards setting up a go-ahead touchdown.