The 2020–21 American Eagles women's basketball team represented the American University Eagles during the 2020–21 NCAA Division I women's basketball season.

The Eagles were by eighth-year head coach Megan Gebbia and played their home games at Bender Arena as members of the Patriot League.

They advanced to the Quarterfinals of the Patriot League tournament before losing to Boston University.

The tournament was cancelled after the Quarterfinals due to the COVID-19 pandemic.

[1] The NCAA tournament and NIT were also cancelled due to the pandemic.