The 2020–21 Kansas State Wildcats women's basketball team represented Kansas State University in the 2020–21 NCAA Division I women's basketball season.
The Wildcats were led by seventh-year head coach Jeff Mittie.
They played their home games at Bramlage Coliseum in Manhattan, Kansas and were members of the Big 12 Conference.
As the tenth seed in the Big 12 Tournament the defeated Texas Tech in the First Round before losing to West Virginia in the Quarterfinals.
They were scheduled to be the fifth seed in the Big 12 Tournament, but it was cancelled before it began due to the COVID-19 pandemic.