The 2020–21 Moldovan Women Top League was the 21st season of the highest women's football league in Moldova.
The competition started on 27 September 2020 and ended on 6 June 2021.
The 8 teams will play a round-robin tournament whereby each team plays each other twice, once at home and once away.
Thus, a total of 56 matches will be played, with 14 matches played by each team.