The 2020–21 Nebraska Cornhuskers women's basketball team represented the University of Nebraska during the 2020–21 NCAA Division I women's basketball season.

The Cornhuskers, led by fifth year head coach Amy Williams, played their home games at Pinnacle Bank Arena and were members of the Big Ten Conference.

As the eight seed in the Big Ten women's tournament they defeated Minnesota in the Second Round before losing to eventual champions Maryland in the Quarterfinals.

They lost in the second round of the Big Ten women's tournament to Michigan.

The NCAA tournament and WNIT were cancelled due to the COVID-19 outbreak.