The NSAA Boys and Girls State Basketball Championship was held in the Coliseum until it also moved to the Devaney Center, and later to Pinnacle Bank Arena.

After the completion of the NU Sports Complex in 1976, the Coliseum primarily served as the home venue of Nebraska's volleyball team, undergoing numerous renovations to tailor the facility specifically to the needs of the program.

Nebraska set a national record with their eighty-eighth consecutive home win in 2009,[3] a streak that ended at ninety when UCLA defeated NU in front of an NCAA regular season-record crowd of 13,870.

[7] The Coliseum is no longer the primary home venue for any of NU's athletic programs, though it is used as an extra practice facility and as office space by Nebraska's gymnastics teams.

[8] The Coliseum hosted various non-sporting events early in its history, including an Elvis Presley concert in 1956, an address by then-Vice President Richard Nixon in 1960, and a speech by United States Senator Robert F. Kennedy during his 1968 presidential campaign, just two months before his assassination.