Oklahoma earned the #4 seed in the College Football Playoff, but fell to LSU 28–63 in the Peach Bowl.

2019 Preseason All-Big 12[2] There was only one head coaching change in the conference following the conclusion of the 2019 season.

[4] *Includes record from tenure at Oklahoma State The regular season will begin on September 12, 2020 and will end on December 5, 2020.

As of August 8, 2020, fourteen non-conference games involving a Big 12 team have been canceled due to the pandemic.

This is a list of the Power Five conferences teams (ACC, Big Ten, Pac-12, Notre Dame, BYU and SEC).

Due to the COVID-19 pandemic, The Big 12 had eleven scheduled games against Power Five conferences, however, each one was canceled.

[11] The Big Ten and Pac 12 have postponed fall sports due to COVID-19 concerns.

On August 8, the MAC announced the postponement of all fall sports for the 2020 season, including football.

[13] On August 10, the Mountain West followed the MAC as the second Group of Five conference to postpone fall sports indefinitely.

[16][17] UMass announced that they would opt of playing fall football and hopes to construct a season in spring 2021.

N23 Ronnie Perkins, OU, DE, Jr. N30 Latrell Bankston, ISU, DL, Jr. D7 Amen Ogbongbemiga, OSU, LB, R-Sr. D14 C.J.