The Tigers competed in the Atlantic Coast Conference (ACC) and were led by head coach John Rittman.

On March 12, it was announced that the 2020 NCAA tournament would be canceled due to the pandemic.

[2] Clemson University suspended all events until April 5, 2020.

[3] On March 17, the ACC cancelled all spring athletic activities and thereby ended the softball season.

[4] The Tigers finished the season 19–8 and 5–1 in ACC play.