The 2020 South Carolina Gamecocks softball team represented the University of South Carolina in the 2020 NCAA Division I softball season.

The Gamecocks played their home games at Carolina Softball Stadium.

The Gamecocks went 2–2 in the Tallahassee Regional during the 2019 NCAA Division I softball tournament.

The SEC preseason poll was released on January 15, 2020.

[2] *Rankings are based on the team's current ranking in the NFCA poll.