The 2020 Colorado Buffaloes football team represented the University of Colorado Boulder during the 2020 NCAA Division I FBS football season.

The Buffaloes were led by first-year lead coach Karl Dorrell and played their home games on campus at Folsom Field as a member of the South Division of the Pac-12 Conference.

On August 11, 2020, the Pac-12 Conference suspended all fall sports competitions due to the COVID-19 pandemic.

On September 3, the Pac-12 announced a resumption of the 2020 football season featuring a seven-game conference-only schedule, starting on November 7 and ending with the Pac-12 Championship game on December 18.

The Pac-12 then announced that Colorado would instead play San Diego State in a non-conference game at home on November 28.