Led by second-year head coach Todd Stepsis, the Bulldogs compiled an overall record of 2–3 with an identical mark in conference play, placing fifth in the PFL.

The team played its home games at Drake Stadium in Des Moines, Iowa.

[1][2] A replacement game, scheduled for the same day, was announced against Black Hills State on July 14.

[3] On July 27, that replacement game, along with Drake's scheduled games against North Dakota State and Dixie State, were canceled due to the Pioneer Football League's decision to play a conference-only schedule due to the COVID-19 pandemic.

[5][6] Following the decisions by Marist and Dayton to opt out of a spring season, the PFL released another schedule in February 2021.